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Factor II (Prothrombin) Mutation
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Factor II (Prothrombin) Mutation

Test name:
Factor II (Prothrombin) mutation

Order name:
FII MUT

Specimen requirements:
EDTA Peripheral blood

Minimum volume:
0.5 mL

Storage and stability information:
Room temperature, 1 week

Test performed:
Once per week

Methodology:
PCR, Invader assay

Reference range:
Negative for the Factor II Prothrombin G20210A mutation

Clinical significance:
Factor II Mutation (G20210A) is a most common cause of venous thrombosis. Assessment of Factor II (Prothrombin) G20210A is useful in patients with thromboembolism, deep vein thrombosis or pulmonary embolism. Carriers of the mutation have a 3-fold increased risk. Other mutations and other risk factors (ex. contraceptive use) compound the risk for venous thrombosis.

CPT codes:
81240


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