ALK by FISH

Test name:
ALK by FISH

Order name:
ALK by FISH request

Specimen requirements:
Formalin fixed paraffin-embedded tissue (FFPE)

Minimum volume:
FFPE – 2 unstained 4µm thick sections on positively charged slides plus 1 stained H&E slide of the same block

Storage and stability information:
Room temperature

Test performed:
Twice per week

Methodology:
Fluorescence in situ hybridization

Reference range:
See lab report

Clinical significance:
Abnormalities of ALK are present in 2 to 7% of non-small-cell lung cancers.  Patients with rearrangements of ALK are eligible for treatment with the ALK inhibitor, XALKORI® (crizotinib).

CPT codes:
88368 x 2