Crohn's Disease

You told us that you are years old. Crohn's disease happens most often in people who are ages 15 to 35. Although Crohn's disease happens more often in this age group, it may happen at any age.

You told us you have a parent, sibling, or child (first-degree relative) with Crohn's disease. Crohn's tends to run in families because the condition has a genetic component. People with brothers, sisters, parents, or children with Crohn's disease have a higher risk of developing the disease than other people. Family history of the condition is the biggest risk factor for developing it. Children of parents with Crohn's disease tend to develop Crohn’s at an earlier age than other people. Remember to share your family history with your health care provider.

You told us you have a grandparent, uncle, aunt, nephew, niece, half-brother, or half-sister (second-degree relative) with Crohn's disease. Crohn's tends to run in families because the condition has a genetic component. People with a second-degree relative with Crohn's are at higher risk for developing the disease. Family history of the condition in second-degree relatives is the second biggest risk for developing it. Remember to share your family history with your health care provider.

You told us that you are of Eastern European Jewish (Ashkenazi) decent. People with this ethnic background are 4 to 5 times likely to develop Crohn's disease. Remember to share your family history with your health care provider.

You don’t have a first- or second-degree relative with Crohn's disease and you aren’t of eastern European Jewish ancestry. Many older studies showed that Crohn's disease occurs more often in Caucasians than in other racial or ethnic groups. But more recent studies show that this may no longer be true. For example, in some areas of the U.S. the rate of Crohn's in African Americans is nearing that of Caucasians. Crohn's disease is less common in Asian Americans, Hispanic Americans, and American Indians, compared with Caucasians. These differences may be tied to environmental factors instead of to ethnic or racial backgrounds. Some of these environmental factors are discussed elsewhere in these results.

You told us that you are a smoker. Smoking makes it roughly twice as likely that you’ll get Crohn's disease. Smoking also makes Crohn’s symptoms worse. In particular, flare-ups are more common and more severe. Smoking also may make Crohn’s come back after surgery. Former smokers are also at risk for Crohn’s, but the risk is lower. Talk with your health care provider about programs that can help you quit.

You told us that you have been a smoker. Smoking makes it roughly twice as likely that you’ll get Crohn's disease. Smoking also makes Crohn’s symptoms worse. In particular, flare-ups are more common and more severe. Smoking also may make Crohn’s come back after surgery. Former smokers are also at risk for Crohn’s, but the risk is lower.

You told us you don’t smoke and haven’t smoked in the past. Smoking makes it roughly twice as likely that you’ll get Crohn's disease. By not smoking you have cut your risk of developing Crohn's.

You told us you had your appendix removed (appendectomy) less than 1 year ago. People who have had their appendix removed in the last year are about 7 times more likely to develop Crohn’s disease. After 5 years, this risk falls to the same risk as for other people. Researchers don’t think the appendectomy causes Crohn’s disease. Rather, they think the risk is higher because the symptoms of Crohn’s and appendicitis are so similar. A health provider may remove an appendix to relieve symptoms that were really caused by Crohn’s. Remember to tell your health care provider about any surgeries and procedures you’ve had.

You told us you had your appendix removed (appendectomy) between 1 and 5 years ago. People who have had their appendix removed within that period are about 2 times more likely to develop Crohn’s disease than other people. After 5 years, this risk falls to the same risk as for other people. Researchers don’t think the appendectomy causes Crohn’s disease. Rather, they think the risk is higher because the symptoms of Crohn’s and appendicitis are so similar. A health provider may remove an appendix to relieve symptoms that were really caused by Crohn’s. Remember to tell your health care provider about any surgeries and procedures you’ve had.

You told us you had your appendix removed (appendectomy) more than 5 years ago. Although people who have their appendix removed are more likely to develop Crohn’s disease shortly after the surgery, that risk drops after 5 years. Your current risk is the same as that for people who haven’t had their appendix removed. Researchers don’t think the appendectomy causes Crohn’s disease. Rather, they think the risk is higher because the symptoms of Crohn’s and appendicitis are so similar. A health provider may remove an appendix to relieve symptoms that were really caused by Crohn’s.

The environment you live in may also play a role. Crohn's disease seems to be more common in developed countries than in undeveloped countries. It is also more common in cities and industrial areas instead in rural areas. It’s also more common in northern countries than southern countries in the Northern Hemisphere. Researchers aren’t sure why this is so. They think these variations in location may be because of a “Western” lifestyle. People who live a Western lifestyle eat more meat, are exposed to more pollution and more industrial chemicals. Another reason that Crohn’s is more common in these areas may be because people who live there may have doctors who can better diagnose the condition.

Crohn’s disease has no cure. But several treatments are available that can ease and control symptoms of the condition. Treatment may also bring about remission in some cases. This can allow a person with Crohn’s to lead a full life.

People with Crohn’s are at risk for early small bowel and colorectal cancer. If you have Crohn’s, talk with your health care provider about getting checked for these cancers.

This information is not intended as a substitute for professional health care. Always talk with a health care provider for advice concerning your health. Only your health care provider can figure out if you have Crohn's disease.