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Antiparietal cells antibodies test

Definition

An antiparietal cells antibodies test is a blood test that looks for antibodies against the parietal cells of the stomach. The parietal cells make and release a substance that the body needs to absorb vitamin B12.

Alternative Names

APCA; Anti-gastric parietal cell antibodies

How the test is performed

A blood sample is needed. For information on how this is done, see:

How to prepare for the test

No special preparation is necessary.

Why the test is performed

Your health care provider may use this test to help diagnose pernicious anemia. Other tests are also used to help with the diagnosis.

Normal Values

A negative result is normal.

What abnormal results mean

A positive test result is abnormal. This may be due to:

What the risks are

Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight but may include:

  • Excessive bleeding
  • Fainting or feeling light-headed
  • Hematoma (blood accumulating under the skin)
  • Infection (a slight risk any time the skin is broken)

References

Antony AC. Megaloblastic anemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 170.


Review Date: 2/5/2012
Reviewed By: Todd Eisner, MD, Private practice specializing in Gastroenterology, Boca Raton, FL. Olinical Instructor, Florida Atlantic University School of Medicine. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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