BEACON EMR HIPAA Disclaimer Site Map Social Media
BayCare Health System
Community Benefit Financial Assistance Policy Quality Report Card Health Library News Dr.BayCare Find Us
Services Hospitals Find A Doctor Classes & Events About Us Careers Contact Us Get E-Newsletter
CCND1-IGH t(11;14) by FISH
 Back  Back


May We Help You?
 

Call 1-877-692-2922
Monday-Friday, 8am to 5pm

Persons with hearing and speech disabilities can reach the above number through TDD and other specialized equipment by calling the Florida Relay Service at 711.

Contact Us
Send 
e-mail
Search jobs


Decrease (-) Restore Default Increase (+) Font Size
Print    Email

CCND1/IGH t(11;14) by FISH

Test name:
FISH, CCND1/IGH t(11;14)

Order name:
t(11;14) by FISH request

Specimen requirements:
Sodium heparin peripheral blood or bone marrow. Formalin fixed paraffin-embedded tissue (FFPE)

Minimum volume:
1mL blood or bone marrow. FFPE – 2 unstained 4µm thick sections on positively charged slides plus 1 stained H&E slide of the same block

Storage and stability information:
Room temperature 3 days for blood and bone marrow. FFPE at room temperature indefinitely.

Test performed:
Twice per week

Methodology:
Fluorescence in situ hybridization

Reference range:
See lab report

Clinical significance:
The t(11;14) translocation leads to juxtaposition of the Immunoglobulin Heavy Chain loci with the CCND1 (Cyclin D1) gene and is found in almost all cases of mantle cell lymphoma.  The t(11;14) is not specific for mantle cell lymphoma however, as it can be identified in other B-cell neoplasms, including plasma cell myeloma.

CPT codes:
88368 x 2


Serving The Tampa Bay Area © Copyright 2014 BayCare Health System