BEACON EMR HIPAA Disclaimer Site Map Social Media
BayCare Health System
Community Benefit Financial Assistance Policy Quality Report Card Health Library News Doctor Connect Find Us
Services Hospitals Find A Doctor Classes & Events About Us Careers Contact Us Get E-Newsletter
Myeloma Panel by FISH
 Back  Back

May We Help You?

Call 1-877-692-2922
Monday-Friday, 8am to 5pm

Persons with hearing and speech disabilities can reach the above number through TDD and other specialized equipment by calling the Florida Relay Service at 711.

Contact Us
Search jobs

Decrease (-) Restore Default Increase (+) Font Size
Print    Email

Myeloma Panel by FISH

Test name:
Myeloma panel by FISH (CEP 5/9/15, del13q14, IGH, t(11;14), TP53) 

Order name:
Myeloma panel by FISH request

Specimen requirements:
Sodium heparin peripheral blood or bone marrow

Minimum volume:
1 mL

Storage and stability information:
Room temperature 3 days

Test performed:
Twice per week

Fluorescence in situ hybridization

Reference range:
See lab report

Clinical significance:
Chromosomal abnormalities are found in 30-50% of patients with multiple myeloma. The abnormality detection rate is greatly increased by FISH analysis.  Using FISH, aneuploidy is detected in 67-90% of cases, while rearrangements of IGH translocations are found in at least 65-70% of patients with the t(11;14) translocation representing 10%.  Deletions of 13q or loss of chromosome 13 are found by FISH in 20-30% of patients.  These abnormalities are associated with a significant lower rate of response to conventional chemotherapy and to a shorter survival.  Deletions of TP53 are also known to have a poor prognosis.

CPT codes:
88368 x 11

Serving The Tampa Bay Area © Copyright 2014 BayCare Health System